Treatment of triple-negative breast cancer with Chinese herbal medicine

نویسندگان

  • Hui Meng
  • Nan Peng
  • Mingwei Yu
  • Xu Sun
  • Yunfei Ma
  • Guowang Yang
  • Xiaomin Wang
چکیده

INTRODUCTION Triple-negative breast cancer (TNBC) is featured with the biological properties of strong aggressive behaviors, rapid disease progression, high risk of recurrence and metastasis, and low disease free survival. Patients with this tumor are insensitive to the endocrine therapy and target treatment for HER-2; therefore, chemotherapy is often used as routine treatment in clinical. Because of the fact that a considerable number of patients seek for Chinese herbal medicine (CHM) treatment after operation and chemotherapy and (or) radiotherapy, it is thus need to evaluate the correlation between Chinese herbal medicine treatment and prognosis. METHODS AND ANALYSIS This is a multicenter, prospective cohort study started in March 2016 in Beijing. A simple of 220 participants diagnosed with TNBC were recruited from nine hospitals and are followed up every 3 to 6 months till March 2020. Detailed information of participants includes personal information, history of cancer, quality of life, symptoms of traditional Chinese medicine and fatigue status is taken face-to-face at baseline. ETHICS AND DISSEMINATION The study has received ethical approval from the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University (No.2016BL-014-01). Articles summarizing the primary results and ancillary analyses will be published in peer-reviewed journals. TRIAL REGISTRATION Chinese Clinical Trial Registry: ChiCTR-OOC-16008246.

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عنوان ژورنال:

دوره 96  شماره 

صفحات  -

تاریخ انتشار 2017